The Helleday Laboratory proudly presents a novel concept of treating cancer, based on a general non-oncogene addition in cancer cells. The new concept is that cancer cells are killed by their own high level of intrinsic oxidative stress, not present in normal cells. We target the MTH1 protein required to prevent oxidative stress in cancer to become DNA damage. Normal cells have low level of oxidative stress and don’t need the MTH1 protein. See how the concept works!
Learn more about MTH1 and our revolutionary anti-cancer approach here: http://www.helleday.org


All faculty members have a track record of academic excellence and joined BRFAA from leading US and European Research and Clinical Centers. Their different expertise complement each other beautifully and result in a powerful scientific team. More than 300 postdoctoral fellows, laboratory technicians, and Ph.D. students work closely with the faculty to unravel the mechanisms behind fundamental human diseases such as diabetes, cancer, Alzheimer’s, cardiomyopathies etc. The Foundation is also fortunate to have a talented and dedicated administrative staff that supports the research and helps make this complex organization work smoothly and effectively. Everyone at BRFAA is committed to scientific excellence and integrity in all that they do and are dedicated to making a positive impact on improving human quality of life.







